Drinking on Ozempic: Tips for Sipping Without Slipping

Drinking on Ozempic

So you’ve joined the Ozempic club, or are thinking about it. Congrats on managing your type 2 diabetes and perhaps shedding a few pounds in the process. But let’s get real for a second: you want to know if you can still enjoy a cocktail (or three) without turning your life into a medical episode of “Jackass.” Here’s the lowdown on what I’ve learned from real life experience and tips on how to sip smart without slipping into chaos.

I like to drink. I really do. It’s my vice of choice–okay one of my vices. Y’all already know food is my first which is how I ended up weighing 243 pounds.

But back to drinking.

Sometimes it’s wine, most times it’s a good ass margarita on the rocks with salt on the rim. Just writing about it makes me want one, right now!

I’ve noticed that since I started using Ozempic, I can’t really drink anymore. Ugh.

Ozempic 101: The Wonder Drug

Ozempic, the fancy-pants name for semaglutide, is here to regulate your blood sugar like a strict parent at a school dance. It nudges your body to produce insulin, curbs that pesky glucagon, and slows down your digestion so you’re not wolfing down snacks like a gremlin. But mix it with alcohol, and you’ve got a recipe for a blood sugar rollercoaster.

It became really apparent to me recently when at a dinner party, I ordered a light margarita and then forgot that I was supposed to be drinking light margaritas and started drinking the regular margaritas in the pitcher with the rest of the group.

I must’ve had about four margaritas and I swear fo’ God I thought I was going to call Earl in Risha’s car going home and with her driving that’s easy enough to do without drinking, lol. Risha doesn’t drink so I rode to the restaurant with her so that I could.

I remember thinking to myself, damn girl you are so messed up. I was mad af about it too because I do not like that sick drunky feeling. Uh uh, I am too old for that.

When I finally came to the next day, in full makeup, contacts, and my hair not in a bonnet sprawled across my bed, it dawned on me where I had slipped up. I forgot to drink the light margaritas.

Alcohol and Ozempic: The Frenemy Duo

Alcohol is that frenemy who promises fun but delivers hangovers and bad decisions. When you’re on Ozempic, alcohol can mess with your blood sugar levels, making them plummet.

I am still in my trial-and-error mode with drinking and Ozempic. I don’t want to give up my boozy pleasures altogether. I’ve been testing out my theory of drinking light margaritas and that was working. I can usually have one whole one and one that I sipped on until the ice completely watered it down and I was drinking margarita flavored water. Currently, that’s my new limit.

When it comes to wine, I am basically limited to one glass now.

Here’s what I am learning.

1. Know Your Limits (Seriously, Know Them)

You’ve heard it before, but moderation really is key here. Your body is already handling the metabolic circus thanks to Ozempic, so drowning it in booze is like adding fuel to the fire. I find it’s best to stick to one or two drinks. Yes, just one or two.

2. Eat

>Remember those times when you drank on an empty stomach and regretted it? Yeah, don’t do that. Eating before or while drinking can help stabilize your blood sugar. Go for something with carbs and protein. I seem to want to eat more than usual while drinking on Ozempic.

3. Avoid Sugar Bombs

I love a fruity cocktail, but they’re sugar bombs waiting to sabotage my blood sugar levels. If I were smarter, I’d opt for drinks with no sugar.  My compromise with myself was switching to drinking light margaritas. A glass of wine, a light beer, or a spirit with soda water can be your new best friends.

4. Hydrate Like It’s Your Job

Alcohol dehydrates you. Ozempic can make you feel queasy. Yes, it can! Combine the two, and you’re setting yourself up for a hangover from hell. Drink water between alcoholic beverages. Yes, water. It’s not glamorous, but neither is vomiting at brunch.

5. Monitor Your Blood Sugar

You gotta keep an eye on your blood sugar levels before, during, and after drinking. The last thing you need is a surprise hypo episode ruining your night (and your dignity).

6. Have a Backup Plan

Make sure someone knows you’re on Ozempic, carry some fast-acting carbs like glucose tablets, and don’t be a hero. If you feel off, seek help.

True story.

Some years before I got on Ozempic when I was much heavier, I was out at a restaurant and made the mistake of eating a slice of cheesecake and drinking a margarita.

When I got home, I felt clammy, started to sweat, and within minutes, my clothes were fully drenched and I literally passed out on the bathroom floor.  Luckily my best friend was there and she helped me come to.  When I regained consciousness, and thanked God I was still alive, I climbed in the bed and went to sleep.  Later when I told my doctor what happened, she said I should have gone to the hospital and that I had a hyperglycemia episode.  

So, I speaketh from experience.


I don’t know how I managed to give the speech I did at that dinner party Friday night as messed up as I was, but when I went back and looked at the video the next day, I impressed my own damn self. Go ‘head girl!

I know Ozempic has caused a lot of folks to stop drinking outright. It can have that effect on you. I am not there yet and I hope I never will be. I am a Friday evening through Sunday late afternoon kind of drinker. During the week it’s usually just wine and nothing stronger in the evening. But being on Ozempic has really slowed my weekday drinking down considerably.

For folks thinking about being Ozempic who love a good drink, this is something you are really going to have to take into consideration–depending on how much you drink and what you drink.

Typically, dopamine is released when you drink alcohol, activating your brain’s reward system and giving you that warm fuzzy feeling. While you’re taking Ozempic, however, GLP-1 targets in the reward centers of your brain block dopamine bursts, lessening that good feeling that comes with drinking alcohol. If your brain doesn’t reward you for alcohol consumption, your desire to drink may be lower.

I think I am fighting that, lol. I like to drink but I can def tell it makes me feel differently. I don’t get the same warm fuzzy feeling I used to. But like with my addiction to McDonald’s french fries, my body tells me one thing and my brain another.

When it comes to alcohol my body says, girl please, “you gone be sick.” My brain is like, “girl you know you want to drink.”

I also have to take into consideration that as my body absorbs alcohol into my bloodstream through the digestive tract, it can cause irritation in the lining of your stomach and alcohol can slow the rate at which my stomach empties resulting in more nausea, vomiting, and digestive issues.

Luckily for me, I just had really bad nausea Friday night that was gone (thank you God!) by the time I woke up Saturday with no hangover.

I would love to hear how other folks who like to drink and are on Ozempic are handling the side effects? Any tips would be greatly appreciated. Like I said, I am still in my trial-and-error period. Friday night was an error of epic proportion.

I’d also like to hear from folks who have just stopped drinking altogether. How’s that been for you? I don’t want to do that, but if I discover that at some point the light margaritas are too much for me, I may have to.

I pray that is not the case. Will you pray that’s not the case for me too? Nobody wants that for me, not me and not you.

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Disclaimer: I am not a doctor, but I am on Ozempic.  I am sharing my experience to help better yours and to learn from others about their experience.